Smart polymer lateral-flow assay achieves near-PCR sensitivity for decentralized HCV antigen testing
Investigators evaluated SMART-C, a novel lateral-flow assay integrating thermo-responsive smart polymers for HCV antigen extraction, in a prospective multinational study across Egypt, Pakistan, and Japan. Among 1,353 paired clinical samples, the test demonstrated 94.6% sensitivit…
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Molecular Dx
Earlier culture read times at 16 hours maintain identification and susceptibility accuracy in automated microbiology workflows
Significance 5/10 Point of CareCoyote multiplex respiratory POCT assays demonstrate high concordance with laboratory comparators
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Significance 4/10 BiomarkersPlasma succinate identifies SDHx deficiency and correlates with tumor burden
Significance 5/10 Molecular DxAI enhances interpretation and experimental design across routine molecular assays
Significance 3/10 Point of CareNaked-eye LAMP protocol enables rapid Chikungunya virus detection
Significance 3/10 BiomarkersFABP1 functions as an active metabolic buffer rather than a passive injury marker in kidney stones
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Significance 5/10 Molecular DxValidated multiplex qPCR panel detects 25 tick-borne pathogens in clinical and surveillance samples
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Significance 4/10Focus areas
All focus areasDiagnostics for the developing world and the themes that decide access, from newborn screening to WHO guidance.
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Open the LibraryThe highest-significance landmark studies in the diagnostics library.
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