Mass Spectrometry

Molecular Rapid Diagnostics with Stewardship Are Cost-Effective for Bloodstream Infections Clinical microbiology reviews 2018 Landmark-class Rapid Blood Culture Diagnostics with Direct Communication Reduce Time to Targeted Therapy: Systematic Review Clinical microbiology reviews 2016 Landmark-class Systemic Amyloidosis: Advances in Mass Spectrometry Typing and Diagnostic Imaging Lancet (London, England) 2015 Landmark-class FDA Outlines Regulatory Path for Clinical Mass Spectrometry Devices Clinical chemistry 2015 Landmark-class Antimicrobial Resistance Mechanisms in M. tuberculosis: A Translational Framework Clinical microbiology reviews 2026 Significance 7/10 From PKU to Genomics: Six Decades of Newborn Screening Evolution Clinical chemistry 2025 Significance 7/10 Mass Spectrometry Poised to Replace Electrophoresis for M-Protein Detection in Clinical Labs Annals of laboratory medicine 2025 Significance 7/10 VITEK MITUBE Enables Direct MALDI-TOF Identification of Gram-Negative Bacteria from Blood Cultures Without Subculture Journal of clinical microbiology 2025 Significance 7/10 Laboratory Medicine Central to CKD-MBD Management: PTH, Vitamin D, and Bone Turnover Markers Reviewed Clinical chemistry and laboratory medicine 2025 Significance 7/10 Novel Methylglyoxal-Albumin Biomarker Predicts New-Onset Diabetes in Prediabetic Patients Clinical chemistry 2025 Significance 7/10 Solbinsiran siRNA Targeting ANGPTL3 Reduces ApoB in Mixed Dyslipidaemia: Phase 2 Results Lancet (London, England) 2025 Significance 7/10 Exemestane Cross-Reacts with All Androstenedione Immunoassays, Causing Falsely Elevated Results Annals of laboratory medicine 2025 Significance 7/10 Metabolomic Biomarkers Show Promise for Breast Cancer Diagnosis and Prognosis Annals of laboratory medicine 2025 Significance 7/10 Plasma Proteomics Identifies Mortality-Associated Protein Signatures in Sepsis EBioMedicine 2024 Significance 7/10 Mass Spectrometry Transforms Clinical Immunoglobulin Analysis and M-Protein Detection Clinical chemistry 2024 Significance 7/10 Updated Guidance for Processing CF Respiratory Samples in the CFTR Modulator Era Clinical microbiology reviews 2024 Significance 7/10 Laboratory Diagnostics for Endocrine Hypertension: From Current Biomarkers to Omics Clinical chemistry 2024 Significance 7/10 Neural Antibody Testing for Autoimmune CNS Disorders: Assays, Panels, and Clinical Utility Clinical biochemistry 2024 Significance 7/10 Urine Albumin Measurement Standardization Critical for CKD Diagnosis Clinical chemistry 2024 Significance 7/10 Unified Framework Exposes Evidence Gaps in Neurological Protein Biomarkers EBioMedicine 2023 Significance 7/10 Parathyroid Hormone Measurement Evolves from Immunoassay to LC-MS/MS Clinical chemistry and laboratory medicine 2023 Significance 7/10 Cepheid Xpert GBS LB XC Test Validated in Multicenter Study for Prenatal GBS Screening Journal of clinical microbiology 2022 Significance 7/10 LC-MS/MS Operations Guide Covers Validation, QA, and Troubleshooting for Clinical Labs Annals of laboratory medicine 2022 Significance 7/10 Systematic Review Establishes Best Practices for LC-MS/MS Calibration in Clinical Labs Annals of laboratory medicine 2022 Significance 7/10 Bacteroides fragilis Group: Updated Taxonomy, Resistance Trends, and Species-Level Identification Methods Journal of clinical microbiology 2022 Significance 7/10 Radiotheranostics Enter Mainstream Oncology: A Clinical Pharmacology Primer Clinical pharmacology and therapeutics 2022 Significance 7/10 Integrating Computational Pathology and Proteomics to Overcome Tumor Heterogeneity The Journal of pathology 2022 Significance 7/10 Comprehensive Guide to LC-MS/MS Method Development for Clinical Diagnostic Assays Annals of laboratory medicine 2022 Significance 7/10 COVID-19 Pandemic Innovations Fuel Next Generation of Infectious Disease Diagnostics Clinical biochemistry 2022 Significance 7/10 Rapid Antimicrobial Susceptibility Testing: Where Technology Stands and What Is Still Needed Clinical chemistry 2021 Significance 7/10 16S rRNA Gene Sequencing for Bacterial Identification: Performance, Limits, and the Road to NGS Clinical microbiology reviews 2020 Significance 7/10 Mass Spectrometry Outperforms Immunoassays for Cortisol in Cushing's Syndrome Screening Annals of laboratory medicine 2020 Significance 7/10 MALDI Mass Spectrometry: From Principles to Expanding Clinical Applications Clinical chemistry and laboratory medicine 2020 Significance 7/10 New Diagnostics for Invasive Fungal Infections: From Antigen Testing to Molecular Assays and VOC Detection Journal of clinical microbiology 2020 Significance 7/10 Proteomic Mass Spectrometry Expands Its Role Across Pathology and Laboratory Medicine Clinical biochemistry 2020 Significance 7/10 ePlex Fungal Panel Identifies 15 Fungal Pathogens from Blood Cultures with Up to 100% Sensitivity Journal of clinical microbiology 2020 Significance 7/10 ePlex Blood Culture ID Gram-Positive Panel Identifies 20 Pathogens and 4 Resistance Genes with High Accuracy Journal of clinical microbiology 2020 Significance 7/10 Mass Spectrometry Advances as the Gold Standard for Sex Hormone Measurement Clinical biochemistry 2020 Significance 7/10 LC-MS/MS Matures into Routine Clinical Diagnostics After a Decade of Growth Clinical biochemistry 2020 Significance 7/10 Lab Consolidation Enables AI-Driven Genomics and Transformative Diagnostic Platforms Clinical microbiology reviews 2020 Significance 7/10 Clinical Mass Spectrometry Expands Across Pathology Disciplines Journal of clinical pathology 2019 Significance 7/10 Making the Case for Advanced Microbiology Tests: A Framework for Demonstrating Clinical Utility to Payers Journal of clinical microbiology 2019 Significance 7/10 MALDI Imaging Mass Spectrometry Poised to Complement IHC in Pathology Workflows Journal of clinical pathology 2019 Significance 7/10 Mass Spectrometry Serum Disaccharide Assay Shows Promise as Panfungal Diagnostic Across Six European Centers Journal of clinical microbiology 2019 Significance 7/10 Aberrant Glycosylation as a Source of Cancer Biomarkers: Analytical Advances and Clinical Potential Clinical chemistry and laboratory medicine 2019 Significance 7/10 Phenotypic Assays for Carbapenemase Detection: A Practical Laboratory Review Journal of clinical microbiology 2018 Significance 7/10 Fentanyl Analog Detection: Analytical Challenges in the Synthetic Opioid Epidemic Clinical chemistry 2018 Significance 7/10 Point-of-Care Testing Trends: From Wearables and Microfluidics to Mass Spectrometry Clinical chemistry 2018 Significance 7/10 Proteomic Methods Unlock Tumour Heterogeneity Analysis in Archival FFPE Tissues The Journal of pathology 2018 Significance 7/10 Dried Blood Spots Cover Over 2,000 Analytes Across All Major Analytical Platforms Clinical chemistry 2017 Significance 7/10 MALDI-TOF Mass Spectrometry in Clinical Microbiology: Progress and Remaining Challenges Annals of laboratory medicine 2017 Significance 7/10 Oncometabolites Bridge Inborn Errors of Metabolism and Cancer Diagnostics Clinical chemistry 2017 Significance 7/10 MALDI-TOF MS for Positive Blood Cultures: Methods, Performance, and Clinical Impact Journal of clinical microbiology 2017 Significance 7/10 Preanalytical Best Practices for LC-MS Analysis of Blood Specimens Clinical biochemistry 2017 Significance 7/10 Chromogenic Culture Media: A Decade of Innovation Alongside Molecular Diagnostics Clinical microbiology reviews 2017 Significance 7/10 Genomic Evolution of Ductal Carcinoma In Situ: Clonal Models of Invasion The Journal of pathology 2016 Significance 7/10 MALDI-TOF MS Revolutionises Identification of Clinically Important Molds Journal of clinical microbiology 2016 Significance 7/10 FIA-MS/MS Method Validated for Dried Blood Spot Amino Acid Monitoring in Phenylketonuria Management Clinical biochemistry 2016 Significance 7/10 Measuring Monoclonal Proteins: From Electrophoresis Limitations to LC-MS/MS Precision Clinical chemistry and laboratory medicine 2016 Significance 7/10 Mass Spectrometry and Free Light Chain Assays Transform Monoclonal Gammopathy Detection Clinical chemistry and laboratory medicine 2016 Significance 7/10 LC-MS/MS in Therapeutic Drug Monitoring: Current Status and Future Directions Clinical biochemistry 2016 Significance 7/10 MALDI-TOF MS Set to Expand Beyond Microbiology Into Broader Clinical Chemistry Clinical chemistry 2015 Significance 7/10 Ambient Ionization Mass Spectrometry for Real-Time Cancer Diagnosis and Surgical Margins Clinical chemistry 2015 Significance 7/10 IQ Consortium Reviews Human Mass Balance Study Designs Including Microtracer and AMS Approaches Clinical pharmacology and therapeutics 2026 Significance 6/10 Pro-GRP as a Complementary Biomarker for Medullary Thyroid Carcinoma: High Specificity, Lower Sensitivity Than Calcitonin Clinical chemistry and laboratory medicine 2025 Significance 6/10 Non-Diphtheriae Corynebacterium: An Underestimated Clinical Pathogen Requiring MALDI-TOF Identification Journal of clinical microbiology 2025 Significance 6/10 Laboratory Testing for Prenatal Substance Exposure: Methods, Matrices, and Interpretation Pitfalls Clinical chemistry 2024 Significance 6/10 Liquid Biopsy with miRNA and ctDNA Shows Promise for Gastric Cancer Screening and Treatment Monitoring Clinical biochemistry 2024 Significance 6/10 AI Models Show Strong Performance Across Urinalysis Applications Clinical chemistry 2023 Significance 6/10 Immunoassay vs LC-MS for Androgen Measurement: Pitfalls and Clinical Guidance Clinical chemistry 2023 Significance 6/10 Practical Guide to Investigating Lead, Mercury, and Arsenic Poisoning in General Practice Journal of clinical pathology 2022 Significance 6/10 Updated Review: Nocardia Identification Transformed by MALDI-TOF and Whole Genome Sequencing Clinical microbiology reviews 2022 Significance 6/10 Two Decades of Clinical Mass Spectrometry Progress: From Neonatal Screening to Protein Biomarkers Clinical chemistry and laboratory medicine 2022 Significance 6/10 Laboratory Biomarkers for Multiple Sclerosis: From Oligoclonal Bands to Neurofilament Light Clinical biochemistry 2021 Significance 6/10 Cancer-Associated Fibroblasts: Emerging Biomarker and Therapeutic Target in the Tumour Microenvironment Nature reviews. Clinical oncology 2021 Significance 6/10 Culturing the Uncultured: New Strategies for Growing Human Microbiota in the Sequencing Era Clinical microbiology reviews 2020 Significance 6/10 JCTLM Task Force Assesses Metrological Traceability Using Creatinine as a Model Measurand Clinical chemistry and laboratory medicine 2020 Significance 6/10 Comprehensive Review of Cannabinoid Analysis Across Biological Matrices by LC-MS/MS Clinical chemistry 2020 Significance 6/10 Mass Spectrometry Imaging for Predicting Bone Fracture Healing and Cartilage Repair Outcomes Clinical chemistry and laboratory medicine 2020 Significance 6/10 In-House vs. Kit-Based LC-MS/MS Methods: A Practical Guide for Clinical Laboratories Clinical chemistry and laboratory medicine 2020 Significance 6/10 Mass Spectrometry Reveals How Gut Microbial Metabolites Drive Disease Clinical chemistry and laboratory medicine 2020 Significance 6/10 Metabolomics Enters Clinical Pharmacology: Biomarker Discovery to Drug Response Prediction Clinical pharmacology and therapeutics 2019 Significance 6/10 Alternative Medicine Labs Sell Unvalidated Tests With Misleading Interpretations Annals of clinical biochemistry 2019 Significance 6/10 Automated Urinalysis Advances: From Flow Cytometry to MALDI-TOF Pathogen ID Annals of laboratory medicine 2019 Significance 6/10 Serum SETD7 Emerges as Novel Diagnostic Biomarker for Colorectal Cancer EBioMedicine 2018 Significance 6/10 Hair Cortisol Analysis Offers a Unique Window Into Long-Term Stress Hormones Clinical biochemistry 2018 Significance 6/10 Multi-Omics Approaches Open New Avenues for Alzheimer's Disease Biomarker Discovery Clinical biochemistry 2018 Significance 6/10 Experimental Design, Randomisation, and Validation: Foundations for Reliable Biomarker Discovery Clinical chemistry 2018 Significance 6/10 Population Pharmacokinetics of Polymyxin B Characterised by LC-MS/MS Clinical pharmacology and therapeutics 2018 Significance 6/10 Neuropeptides as Biomarkers and Drug Targets in Obesity: From Bench to Bedside Clinical chemistry 2017 Significance 6/10 GBS Detection Modernised With MALDI-TOF, Molecular Assays, and Chromogenic Media Journal of clinical microbiology 2017 Significance 6/10 Cortisol Measurement Across Matrices: Immunoassay Limitations and the LC-MS/MS Advantage Annals of clinical biochemistry 2017 Significance 6/10 Dried Blood Spot Analysis by Mass Spectrometry for Therapeutic Drug Monitoring Clinical biochemistry 2016 Significance 6/10 Ion Mobility Spectrometry Emerges as Rapid Bedside Screening Tool for Clinical Labs Clinical chemistry 2015 Significance 6/10 Mass Spectrometry of Exhaled Breath Nonvolatiles: An Emerging Biomarker Source Clinical chemistry 2015 Significance 6/10 Mass Spectrometry as a Phenotypic Complement to Pharmacogenomics in Precision Medicine Clinical chemistry 2015 Significance 6/10 Mass Spectrometry Delivers Cost-Effective Solutions Across Expanding Clinical Applications Clinical chemistry 2015 Significance 6/10 Ambient Ionization Mass Spectrometry Targets Point-of-Care Diagnostics Clinical chemistry 2015 Significance 6/10 MDMA-Assisted Therapy for PTSD: Phase 3 Trial and Implications for Drug Testing Laboratories Nature medicine 2021 Significance 5/10 Sphingomyelin Profiling Predicts Short-Term Outcomes in Lower Respiratory Tract Infections Clinical chemistry and laboratory medicine 2019 Significance 5/10 Rickettsioses Diagnostics Evolve Beyond Serology With Molecular and MS-Based Methods Journal of clinical microbiology 2018 Significance 5/10 Top-Down Measurement Uncertainty for Tacrolimus by UHPLC-MS/MS: Two Approaches Converge Clinical biochemistry 2018 Significance 5/10 Measuring Vitamin K in Blood: HPLC and LC-MS/MS Methods Compared Clinical chemistry and laboratory medicine 2017 Significance 5/10