Focus area

Maternal & Newborn

Prenatal, perinatal and newborn-screening diagnostics, including dried-blood-spot programmes and non-invasive prenatal testing.

Latest

Biomarkers

Donor age and sex shape MSC secretome signalling · a framework for potency testing

Stem cell research & therapy March 24, 2026

Significance 5/10 Molecular Dx

CRISPR1 System Linked to Virulence and Resistance in Dominant Neonatal GBS Lineage

Frontiers in cellular and infection microbiology March 6, 2026

Significance 5/10

Landmark studies

Maternal & Newborn

58 studies

Prenatal cfDNA Screening Incidentally Detects Occult Maternal Cancer in Nearly Half of Unusual Results The New England journal of medicine 2024 Landmark-class AI-Guided Screening with Digital Stethoscope Doubles Detection of Peripartum Cardiomyopathy Nature medicine 2024 Landmark-class Preimplantation Genetic Testing for Aneuploidy Does Not Improve Cumulative IVF Live-Birth Rates The New England journal of medicine 2021 Landmark-class PAGE Study: Prenatal Exome Sequencing Identifies Genetic Diagnoses in 8.5% of Fetal Anomalies Lancet (London, England) 2019 Landmark-class NeoPIns Trial: Procalcitonin-Guided Decision-Making Safely Reduces Neonatal Antibiotic Duration by 13 Hours Lancet (London, England) 2017 Landmark-class Permethrin-Treated Baby Wraps Cut Childhood Malaria Incidence by 66% in Ugandan RCT The New England journal of medicine 2025 Landmark-class Noninvasive Prenatal Testing for Red Blood Cell and Platelet Antigens Enters Clinical Practice Blood 2025 Landmark-class RSV in Children: Molecular POC Testing and New Prevention Strategies Reshape Clinical Management Lancet (London, England) 2024 Landmark-class PROMISE-EPI: POC Viral Load-Guided Infant Prophylaxis Reduces Postnatal HIV Transmission Lancet (London, England) 2024 Landmark-class Expanded Prenatal cfDNA Screening Detects Aneuploidies, Microdeletions and Monogenic Variants in a Single Test Nature medicine 2024 Landmark-class Adding Dihydroartemisinin-Piperaquine to Co-trimoxazole Cuts Malaria Risk by 55% in Pregnant Women Living With HIV Lancet (London, England) 2024 Landmark-class Cannabis Exposure in Pregnancy Linked to Placental Dysfunction by LC-MS/MS-Confirmed Urine Testing JAMA 2023 Landmark-class Simplexa Congenital CMV Direct PCR Achieves Near-Perfect Agreement for Newborn Screening in Saliva and Urine Journal of clinical microbiology 2023 Landmark-class Beyond Sequence: Epigenomics, Fragmentomics, and Topology Expand Cell-Free DNA Analysis Science (New York, N.Y.) 2021 Landmark-class NTRK Fusions Across Solid Tumours: Biology, Prevalence, and Testing Strategies Human pathology 2021 Landmark-class Preanalytical Guidelines for Circulating Cell-Free DNA Analysis: A Systematic Review Clinical chemistry 2019 Landmark-class Prenatal Cell-Free DNA Testing: How Genomic Screening Transformed Prenatal Care The New England journal of medicine 2018 Landmark-class NHS Implementation Study Shows NIPT for Down Syndrome Reduces Invasive Testing by Thousands Annually BMJ (Clinical research ed.) 2016 Landmark-class Fingerstick Hepatitis B DNA Testing with Xpert Assay Enables Decentralised Viral Load Monitoring Journal of clinical microbiology 2026 Significance 7/10 From PKU to Genomics: Six Decades of Newborn Screening Evolution Clinical chemistry 2025 Significance 7/10 BrECADD Preserves Fertility Significantly Better Than eBEACOPP in Advanced Hodgkin Lymphoma The Lancet. Oncology 2025 Significance 7/10 Lancet Commission: Global Health 2050 Strategy Highlights Diagnostics as Key to Halving Premature Death Lancet (London, England) 2024 Significance 7/10 Lancet RCT: Intravenous Ferric Carboxymaltose Did Not Reduce Anaemia at 36 Weeks in Malawian Pregnancies Lancet (London, England) 2023 Significance 7/10 Cepheid Xpert GBS LB XC Test Validated in Multicenter Study for Prenatal GBS Screening Journal of clinical microbiology 2022 Significance 7/10 Mutation Enrichment Technologies Advance Low-Frequency Variant Detection for Liquid Biopsy Clinical chemistry 2022 Significance 7/10

Show all 58 studies

Lateral Flow Assays: Technology Advances Drive New Era in Infectious Disease Diagnostics Clinical chemistry 2021 Significance 7/10 Point-of-Care Placental Growth Factor Testing Does Not Reduce Maternal Morbidity in Suspected Pre-eclampsia: PARROT Ireland Trial BMJ (Clinical research ed.) 2021 Significance 7/10 Cardiac Biomarkers in Pediatrics: An Undervalued Diagnostic Resource Clinical chemistry 2021 Significance 7/10 qPCR Kit Outperforms Microscopy for Early Detection of Congenital Chagas Disease EBioMedicine 2021 Significance 7/10 Monthly Dihydroartemisinin-Piperaquine Outperforms Sulfadoxine-Pyrimethamine for Malaria Prevention in Pregnancy in Tanzania Clinical pharmacology and therapeutics 2021 Significance 7/10 Ultrasensitive Diagnostics Target the Hidden Reservoir of Asymptomatic Malaria Journal of clinical microbiology 2021 Significance 7/10 Early-Onset Colorectal Cancer: Rising Incidence Demands New Screening and Biomarker Strategies Nature reviews. Clinical oncology 2020 Significance 7/10 LC-MS/MS Matures into Routine Clinical Diagnostics After a Decade of Growth Clinical biochemistry 2020 Significance 7/10 Dried Blood Spots Cover Over 2,000 Analytes Across All Major Analytical Platforms Clinical chemistry 2017 Significance 7/10 FIA-MS/MS Method Validated for Dried Blood Spot Amino Acid Monitoring in Phenylketonuria Management Clinical biochemistry 2016 Significance 7/10 Biomarker-Based POC Tests for Preeclampsia Could Transform Maternal Care in Low-Resource Settings Clinical chemistry and laboratory medicine 2016 Significance 7/10 Multicenter Validation of Clonit Toxoplasma PCR Kit Shows 94.7% Clinical Sensitivity Journal of clinical microbiology 2025 Significance 6/10 Emerging Technologies in Paediatric Laboratory Medicine: From Microassays to Machine Learning Clinical chemistry and laboratory medicine 2024 Significance 6/10 Laboratory Testing for Prenatal Substance Exposure: Methods, Matrices, and Interpretation Pitfalls Clinical chemistry 2024 Significance 6/10 Immunoassay vs LC-MS for Androgen Measurement: Pitfalls and Clinical Guidance Clinical chemistry 2023 Significance 6/10 Cardiac Troponin and BNP Show Untapped Potential for Cardiovascular Risk Assessment in Pregnancy Clinical chemistry and laboratory medicine 2023 Significance 6/10 Two Decades of Clinical Mass Spectrometry Progress: From Neonatal Screening to Protein Biomarkers Clinical chemistry and laboratory medicine 2022 Significance 6/10 Presepsin Emerges as a Promising Early Biomarker for Perinatal Sepsis Detection Clinical chemistry and laboratory medicine 2022 Significance 6/10 Gut Microbiome in Neurological Disorders: Diagnostic Biomarkers and Therapeutic Targets Clinical microbiology reviews 2022 Significance 6/10 Procalcitonin Reference Values Established for Term Pregnancy and Early Postpartum Annals of clinical biochemistry 2021 Significance 6/10 Congenital Dyserythropoietic Anemias: NGS Transforms Diagnosis of Rare Inherited Anemias Blood 2020 Significance 6/10 Comprehensive Review of Cannabinoid Analysis Across Biological Matrices by LC-MS/MS Clinical chemistry 2020 Significance 6/10 IMP3 Plus L1CAM Immunohistochemistry Optimises Grading of Endometrial Carcinomas Human pathology 2019 Significance 6/10 NeuMoDx GBS Assay Matches CDC Culture Method with 96.9% Sensitivity for Antepartum Screening Journal of clinical microbiology 2019 Significance 6/10 Thyroid Laboratory Testing: A Practical Guide to Pitfalls and Clinical Interpretation Annals of laboratory medicine 2019 Significance 6/10 GBS Detection Modernised With MALDI-TOF, Molecular Assays, and Chromogenic Media Journal of clinical microbiology 2017 Significance 6/10 Toxoplasma ELITe MGB Commercial PCR Kit Shows 89% Sensitivity but Extraction Method Matters Journal of clinical microbiology 2017 Significance 6/10 Dried Blood Spot Analysis by Mass Spectrometry for Therapeutic Drug Monitoring Clinical biochemistry 2016 Significance 6/10 Mass Spectrometry Delivers Cost-Effective Solutions Across Expanding Clinical Applications Clinical chemistry 2015 Significance 6/10 Hypertriglyceridaemia: Genetic Diagnosis and the Role of NGS in Lipid Disorders Journal of clinical pathology 2022 Significance 5/10 Biochemistry of the Menopause: Diagnostic Assays and Hormone Reference Intervals Annals of clinical biochemistry 2017 Significance 5/10 Network Meta-Analysis: High-Dose Psilocybin Outperforms Placebo for Depression, But Effect Is Small BMJ (Clinical research ed.) 2024 Significance 4/10 Novel HK1 Variant Identified as Cause of Hereditary Hemolytic Anemia via Whole-Exome Sequencing Journal of clinical pathology 2020 Significance 4/10