NEJM Review: The Current and Future State of AI Interpretation of Medical Images

This comprehensive NEJM review examines the trajectory of AI in medical image interpretation, covering the evolution from early convolutional neural networks to foundation models. It addresses current FDA-cleared applications, the challenges of generalizability and bias, regulatory considerations, and the shifting role of clinicians as AI tools become integrated into diagnostic workflows. The review serves as a definitive reference for the current state of the field.