Pilot Ring Trial for Plasma ctDNA EGFR Mutation Testing Using Cobas Platform

This pilot proficiency-testing ring trial evaluated the performance of the Cobas EGFR Mutation Test on plasma ctDNA samples across clinical diagnostic laboratories. The study represents an early effort to standardise external quality assessment for liquid biopsy-based companion diagnostics, an area where inter-laboratory harmonisation is critical for reliable treatment selection in non-small cell lung cancer.