POC Glucose Metre Matches Blood Gas Analyser Accuracy Across All Neonatal Gestational Ages
A Japanese multicentre study compared 2,943 blood glucose measurements from the Glutest Mint II point-of-care metre with a blood gas analyser in 285 infants across six NICUs, spanning very preterm to full-term neonates. The POC device showed strong correlation with the reference method, with no clinically significant interference from neonatal-specific factors such as haematocrit and bilirubin levels. These results validate the use of this glucose metre for rapid bedside monitoring across the full range of neonatal patients.
The original study
A multicenter study comparing a point-of-care blood glucose metre with a blood gas analyser in infants by the Shikoku Neonatal Medical Research Group.
- Authors
- Kuboi T, Sugino M, Sadamura T, Kawaguchi N, Tadatomo Y, Takada K, et al.
- Journal
- Annals of clinical biochemistry
- Type
- Journal Article, Multicenter Study, Comparative Study
- PMID
- 40022493
Original abstract
BackgroundThere have been no reports on blood glucose metres for measurements in a wide variety of infant patients, from very preterm infants to mature infants and from the early neonatal period onwards. In this study, we evaluated the accuracy of the Glutest Mint II, a point-of-care blood glucose metre, by comparing blood glucose levels measured by this device with those measured by a blood gas analyser in infants of all gestational ages and birth weights at a number of time points after birth.MethodsInfants aged 22 weeks and 0 days of gestation or older who were born at any of six tertiary neonatal intensive care units between March 2022 and January 2023 and needed blood glucose monitoring were enrolled. Samples were collected into capillary tubes when the physician determined that a blood glucose test was necessary and could be taken at any time after birth and any number of times from the same individual. Blood glucose was measured using a Glutest Mint II and then using a blood gas analyser.ResultsIn total, 2943 blood glucose points were measured in 285 infants. Blood glucose levels measured using the Glutest Mint II were significantly correlated with those measured using a blood gas analyser. Neonatal-specific parameters such as hematocrit and total serum bilirubin levels may not have an effect.ConclusionsThe Glutest Mint II device can measure blood glucose levels with very high accuracy in the range used in the neonatal setting, comparable to the blood gas analyser.