Lab Medicine Significance 5/10

Practical Guidance for Clinical Microbiology Laboratories: Diagnosing Ocular Infections

This updated Cumitech guidance document reviews preanalytic, analytic, and postanalytic aspects of ocular infection diagnosis for clinical microbiology laboratories. It addresses the unique constraints of ophthalmic specimens, describes common and neglected ocular infections, and emphasises the essential collaboration between laboratorians and ophthalmologists for optimal diagnostic care.

The original study

Practical Guidance for Clinical Microbiology Laboratories: Diagnosis of Ocular Infections.

Authors
Leal SM, Rodino KG, Fowler WC, Gilligan PH
Journal
Clinical microbiology reviews
Type
Journal Article, Review
PMID
34076493
Read the original study →

Original abstract

The variety and complexity of ocular infections have increased significantly in the last decade since the publication of Cumitech 13B, Laboratory Diagnosis of Ocular Infections (L. D. Gray, P. H. Gilligan, and W. C. Fowler, Cumitech 13B, Laboratory Diagnosis of Ocular Infections, 2010). The purpose of this practical guidance document is to review, for individuals working in clinical microbiology laboratories, current tools used in the laboratory diagnosis of ocular infections. This document begins by describing the complex, delicate anatomy of the eye, which often leads to limitations in specimen quantity, requiring a close working bond between laboratorians and ophthalmologists to ensure high-quality diagnostic care. Descriptions are provided of common ocular infections in developed nations and neglected ocular infections seen in developing nations. Subsequently, preanalytic, analytic, and postanalytic aspects of laboratory diagnosis and antimicrobial susceptibility testing are explored in depth.