Liquid Biopsy Significance 5/10

Patient-specific physician alerts modestly boost colorectal cancer screening uptake

A cluster-randomised trial in France tested whether notifying GPs about individual non-adherent patients would increase fecal immunochemical test (FIT) participation. Patient-specific reminders yielded a small but significant 4.2% absolute increase in screening uptake at one year compared with usual care, while generic regional adherence reminders had no measurable effect. The results highlight that personalised outreach can improve screening programme performance.

The original study

Effect of Physician Notification Regarding Nonadherence to Colorectal Cancer Screening on Early Cancer Detection.

Authors
Schmeltz H, Rat C, Pogu C, Bianco G, Cowppli-Bony A, Gaultier A, et al.
Journal
JAMA
Type
Letter, Randomized Controlled Trial
PMID
32543677
Read the original study →

Original abstract

This cluster randomized clinical trial compares the effect of physician notification for colorectal cancer screening and cancer detection on patients who were in a patient-specific reminders group in which physicians received a list of nonadherent patients, in a generic reminders group in which physicians received general information about regional screening adherence, or in a usual care group in which physicians received no reminders.